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doi: 10.3945/an.113.003855 220 NuszkiewiczJSutkowyPWrblewskiMPawowskaMWesoowskiRWrblewskaJet al

Melatonin effectively alleviates cellular damage and pathological progression in these diseases by regulating mitophagy

mCRPC, metastatic castration-resistant prostate cancer

Therefore, here we only provide a brief summary of the major relevant studies implying NO/peroxynitrite generation as key players of reperfusion injury in organs such as the gut, the liver, the lung, and the kidney