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11 Low testosterone Potential causes Potential causes of low testosterone levels are: 7 Aging Certain medications Chemotherapy Hypothalamus-pituitary axis disorders Primary hypogonadism Cryptorchidism Orchitis Genetic disorders such as Klinefelter and Kallmann syndrome Symptoms A study in 2020 that investigates the effect of low testosterone in adolescents and young adults suggested that signs of low testosterone are: 12 Low sexual desire and activity Gynecomastia Delayed sexual development Small testes Loss of body hair Complications Testosterone deficiency also can lead to erectile dysfunction, fragile bone, anemia, poor concentration, and memory as well as physical performance