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pif4 plants treated with 0.2 mM BSO show reduced hypocotyl elongation at 27C, suggesting another PIF4-independent thermomorphogenesis pathway that requires normal GSH level (Supplemental Figure 3)

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During this adaptive process, cellular metabolic phenotypes shift accordingly by either increasing OXPHOS flux or enhancing glycolytic dependence to meet the energy demands imposed by sustained oncogenic signaling [75]