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78 HP 160 CAGRILINTIDE Long-Acting Amylin Analog ALIASES Cagrilintide, AM833, long-acting amylin analog CLASS Synthetic amylin analog once-weekly dual amylin/calcitonin agonist FORMULA CHNO (approx) SEQUENCE 37-residue amylin analog with C20-fatty-acid albumin tether HALF-LIFE ~7 days (once-weekly dosing) ROUTES Subcutaneous (Phase 2/3 clinical) MECHANISM OF ACTION Long-acting amylin analog

In vitro studies demonstrate that BPC-157 promotes survival of cells exposed to various stressors including oxidative damage, toxic substances, and serum deprivation

The interruption of one or any combination of these steps places a person at risk of developing deficiency (Figure 2)

Classified as a Dual Amylin and Calcitonin Receptor Agonist (DACRA)

DIO control mice, JAX cat no