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However, when HepaRG stem-cell derived human hepatocytes were subjected to APAP, the same mechanisms of hepatotoxicity were demonstratedstarting with GSH depletion and moving through protein adduct formation, superoxide and peroxynitrite formation and lysosomal iron uptake into mitochondria

Were more interested in body losses for people on the lower end of normal for total body stores, as theres no need to replenish excess amounts

Agrez M, Chandler C, Thurecht KJ, Fletcher NL, Liu F, Subramaniam G

This result indicates that Dihexa likely protects hair cells by modulating a cell death target