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Other agonists, such as the intestine-specific Fexaramine D (FexD), suppressed colitis-associated cancer (CAC) by restoring FXR signaling, enhancing intestinal barrier integrity, and reducing pro-inflammatory M1-like macrophage infiltration within the TIME ( Conversely, FXR inhibition or functional antagonism demonstrates therapeutic value where FXR activation is detrimental

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This impressive array of cellular and molecular functions has raised considerable interest for the use of this substance as a nutritive supplement and also as a therapeutic agent

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& Florencio, F

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Richard Austin, McMaster University, Canada Updates Copyright 2022 Li, Jin, Luo, Xu, Wu, Zhou, Wang, Xu, Jiao, Wang and Yang

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-20C, 1 month (protect from light) Publications (2) Journal Impact Factor Most Recent Int Immunopharmacol miR-671-5p-enriched exosomes derived from human embryonic stem cells under hypoxia balance oxidative stress homeostasis and macrophage reprogramming to alleviate Legg-Calv-Perthes disease by targeting NOX2

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