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Similarly, -synuclein aggregation can suppress system Xc activity, leading to glutathione depletion, whereas membrane damage caused by ferroptosis may in turn facilitate the intercellular spread of -synuclein

Date of Acceptance: December 13, 2019 Abbreviations: reactive oxygen species, ROS

Moreover, low plasma concentrations of SELENOP have been associated with increased risk of heart failure in a recent population-based, prospective cohort study (16)