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ASTRO 2013, 2013

10.3978/j.issn.2305-5839.2014.08.05 Ann Transl Med

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Animal studies suggest that local or systemic use of deferoxamine may significantly alleviate OA cartilage degradation and inhibit ferroptosis markers in chondrocytes by activating the Nrf2 pathway ( Table 1 ) (168, 169)