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In 2023, Zlotnikov et al

Abstract Evidence is emerging that dysregulation of circulating concentrations of homocysteine, an important intermediate in folate and vitamin B12 metabolism, is associated with autism spectrum disorder (ASD), but comprehensive assessments and correlations with disease characteristics have not been reported

[10] PDC links glycolysis to the citric acid cycle, catalyzing the irreversible oxidative decarboxylation of pyruvate to acetyl-CoA, with carbon dioxide (CO 2 ) release and electron transfer to NAD +

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