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Cell Res 29:787803 Watanabe K, Stringer S, Frei O, Umievi Mirkov M, de Leeuw C, Polderman TJC, van der Sluis S, Andreassen OA, Neale BM, Posthuma D (2019) A global overview of pleiotropy and genetic architecture in complex traits

demonstrated that microbial-derived ATP can stimulate the dendritic cell subpopulation expressing CD70 and CX3CR1 on its surface, which induces the differentiation of Th17 cells [48]