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Thus, the authors demonstrate the presence of GSTM1-1 in liver and conclude that the alkylation and potential irreversible inactivation of this isoform in vivo could contribute to an understanding of the hepatotoxicity associated with zileuton [55]

Chiarugi, C

Improvement to formononetins bioavailability have been sought out through advanced delivery systems including nanoparticles, phospholipid complexes, and self-nanoemulsifying systems, and have enhanced its poor solubility and absorption [128,129,130,131]