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Front Neurol 12:661955

Bibcode:2008PLoSO...3.2819B

In epilepsy, this interplay is evident in models such as the lithium-pilocarpine (Li-Pilo) model of SE, which recapitulates key features of epileptogenesis including altered glucose metabolism (Dank et al., 2022) and mitochondrial bioenergetics with increased markers of oxidative damage (Carrasco-Pozo et al., 2015

doi: 10.1155/2021/9947370 82 MartineauARCatesCJUrashimaMJensenMGriffithsAPNurmatovUet al

Conclusion# NAD+ holds clear advantages over Epitalon in nearly every practical comparison: broader evidence base, human clinical data, multi-hallmark coverage, ease of administration, and commercial accessibility