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Food and Drug Administration approved treatment for APAP induced liver injury ( in vitro and in vivo as possible alternative treatments for APAP induced liver injury ( 2 Effects and mechanism of natural products in acetaminophen-induced hepatotoxicity A number of phytochemicals have been identified to have hepatoprotective activity, such as silymarin for the treatment of liver poisoning, chronic hepatitis and cirrhosis (Table 1)

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