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Factors affecting post-discontinuation outcomes Individual variation in GHK-Cu discontinuation effects stems from multiple factors determining whether benefits persist substantially or decline rapidly toward baseline, helping users predict likely personal outcomes and optimize treatment strategies for maximizing durable improvements requiring minimal ongoing intervention

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Although these neurons also survived after transplantation into the motor cortex, their pattern of axonal projections was markedly different, with reduced innervation of the cortex, striatum, and thalamus (Michelsen et al., 2015)