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Radiation exposure leads to bone marrow myelosuppression, and the neutropenic patient is susceptible to bacteremia from gut bacteria translocation (Waselenko et al., 2004)

MMUT, methylmalonyl-CoA mutase

Am J Clin Nutr 57 , 779S785S

The most accepted hypothesis suggests that chronic inflammatory reaction at the site of injection provides a trigger for subsequent malignant transformation (Hartmann et al., 2015)