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5 Patients with IC/BPS were identified by the presence of ICD-9 code 595.1 ('interstitial cystitis') in the electronic medical record, and the prevalence of the diagnosis was found to be 197 per 100,000 women and 41 per 100,000 men

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Both illustrate how metabolic or toxic stress overwhelms antioxidant defenses and drives oxidative liver injury [17].Exogenous stimuli 2.3 Pathological accumulation of ROS In pathological settings, ROS accumulation can exceed the capacity of antioxidant defenses, triggering a cascade of molecular and cellular damage that perpetuates liver injury