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Development of long-term dendritic spine stability in diverse regions of cerebral cortex

New England Journal of Medicine (2025) The REDEFINE 1 Phase 3 trial was a landmark 68-week, double-blind, randomized study comparing CagriSema (cagrilintide 2.4 mg plus semaglutide 2.4 mg) with semaglutide alone, cagrilintide alone, and placebo in 3,417 adults with obesity or overweight without diabetes

PMID 7808419

Suppression of oxidative stress by beta-hydroxybutyrate, an endogenous histone deacetylase inhibitor

Our data suggests that epitalon can extend telomere length in normal healthy mammalian cells through the upregulation of hTERT mRNA expression and telomerase enzyme activity