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Iannielli A, et al

In addition, inhibiting GPX4 also promote ferroptosis in some malignant tumor cells such as pancreatic ductal adenocarcinoma (Sui et al., 2018), etc

Overall, stem-celland immune-cellderived secretomes offer a multi-modal, low-immunogenic platform to subdue microglial pyroptosis, but rigorous optimization and head-to-head validation are essential before clinical translation