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CMS may remove a cost measure from MIPS based on one or more of the factors, which include that a measure steward is no longer able to maintain the cost measure

ROS further modulate the nuclear factor kappa B (NF-B) pathway (Lingappan, 2018) and induce oxidative modifications of transcription factors (e.g., Nrf2, p53), altering their stability and activity in cancer-related processes (Humpton et al., 2022)