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VP is a rare autosomal dominant inherited disorder resulting from the deficiencies of the mitochondrial enzyme photoporphyrinogen oxidase (PPOX), the sixth enzyme in the haem biosynthesis pathway

Carcinoma matrix controls resistance to cisplatin through talin regulation of NF-kB

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However, Ca 2+ overload (induced by pro-inflammatory cytokines) inhibits these flippases and activates scramblases, resulting in PS exposure on the cell surface (Lanser et al., 2021)