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First, we performed mass cytometry by time-of-flight (CyTOF) on peripheral blood mononuclear cell (PBMC) collected at baseline and following nivolumab plus ipilimumab (Supplementary Figs

After labeling, the neurons were fixed either immediately, or after a further incubation of 6 or 12 h, in their original culture media allowing for epitope internalization

Counseling should include the availability of targeted molecular analysis for confirmation of diagnosis, detection of at-risk parents, prenatal diagnostics, and the natural history of HT-1-affected children prior to and following the availability of NTBC