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Xing Y, Li Z, Chen Y, et al

Figure 3 In male Wistar rats treated with sodium arsenite (up to 150 ppm) or arsenate (up to 200 ppm) for twelve weeks, a differential pattern of dyslipidemia was induced by each arsenic species (67)

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They inhibit the pro-inflammatory enzyme 5-lipoxygenase and MMP-3, which are responsible for breaking down collagen and other molecules involved in joint function, as well as the NF-KB pathway which plays a role in the inflammatory response (12)