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PMID 15286019

Di-AnnexinV 29 was labeled with Alexa-fluor 633 from Molecular Probes (Eugene, OR) according to manufacturers instructions

Critical Safety Gaps for Mental Health Applications Unknown effects on cognitive function, memory, personality, mood stability beyond intended therapeutic effect Long-term impacts on brain chemistry (chronic administration effects unexplored beyond 6 weeks in animals) Potential for psychological dependence or tolerance (not studied systematically) Impacts on developing brains in adolescents and young adults (completely unknown with no pediatric studies) Drug Interactions Pose Serious Concerns BPC-157s simultaneous effects on serotonin, dopamine, GABA, glutamate, and nitric oxide systems create multiple theoretical interaction points with psychiatric medications, yet interactions are not well studied. Specific concerns include: With SSRIs and SNRIs: Risk of serotonin syndrome is genuine

A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis

[DOI] [PubMed] [Google Scholar] 270.Neupane P., Bhuju S., Thapa N., Bhattarai H.K