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Discussion We conducted a meta-analysis integrating 154 metabolites from baseline and on-therapy timepoints across independent epidemiological and interventional cohorts encompassing diverse geographic sites, tumor histologies, and treatment modalities, applying DynForest 36 to address the challenge of modeling high-dimensional, time-dependent metabolomics data in small-sample settings

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These mice are popular with scientists who study heart disease because they are very good at developing atherosclerosis

These growing preclinical studies of individual differences in stress response among inbred rodents further support the link between epigenetic mechanisms and development of individual phenotypes [20, 21, 27]