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Similarly, in HaCaT model, myricetin treatment was associated with the downregulation of T-bet and GATA3 expression, accompanied by decreased levels of IL-4 and IFN-, suggesting a potential role in modulating Th1/Th2-associated immune signaling (Hou et al., 2022)

Erastin can inactivate SLC3A2 and block cysteine import (71)

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Pregnancy is characterised by a physiological increase in systemic and placental oxidative stress driven by heightened metabolic rate, mitochondrial activity, and placental oxygen fluctuations [9,10,11]