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Shimada, Y

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PMID: 10 RouanetMLebrinMGrossFBournetBCordelierPBuscailL

doi: 10.1172/JCI111550

Hepatitis B core (HBc) VLPs are among the most insertion-tolerant carriers due to the inherent flexibility of their spike structures (Pumpens and Grens, 2001), allowing epitopes to be displayed at the N-terminus, C-terminus, or the major immunodominant region (MIR)