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This portion of the titration curve corresponds to a buffer: it exhibits the smallest change in pH per increment of added strong base, as shown by the nearly horizontal nature of the curve in this region

Distinguished by its unique ability to inhibit the ectoenzymatic activity of CD38, Isatuximab diverges from Daratumumab by binding to a distinct epitope on CD38, which encompasses the CD38 ectoenzyme catalytic site

By phase, the phase 2 segment is anticipated to grow at the fastest rate during the predicted time

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