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It has long been recognized that ictal cerebral hypermetabolism is characteristic of seizure disorders, where increased cerebral oxygen (Meyer et al., 1966) and glucose consumption (Ryan et al., 2012

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When searching for potential biomarkers of disease status, it was determined that individuals with konzo did have a higher incidence of albumin carbamoylation, a post-translational modification likely induced by increased exposure to a toxic byproduct of linamarin degradation, cyanate 29

doi: 10.1371/journal.pone.0247060 15 BallatoriN.KranceS.MarchanR.HammondC