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Depletion of beneficial taxa such as Odoribacter (Bacteroidetes) and Lachno Clostridium (Firmicutes), along with increased abundance of pro-inflammatory taxa including Ileibacterium and Olsenella , was associated with reduced SCFA gene expression, downregulation of tight junction proteins (occludin and claudin-1), and microglial activation in the amygdala and arcuate nucleus, indicating gut barrier disruption and neuroinflammation that coincided with anxiety-like behavior

Barriers to effective treatment include the persistent stigma that Medication-Assisted Treatment (MAT) is simply trading one drug for another, despite its reducing harm

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Stefan, M

Post-menopausal bleeding is benign in around 85-90% of cases (often caused by vaginal atrophy), but it occasionally indicates serious conditions, including endometrial cancer