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Deciphering the interplay between cysteine synthase and thiol cascade proteins in modulating Amphotericin B resistance and survival of Leishmania donovani under oxidative stress

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c-Myc increases the levels of glycolytic and PPP enzymes, including LDHA, GLUT1, PKM2, and G6PD [63, 64], and enhances DNL and cholesterol synthesis by transcriptionally activating SREBP1/2 [134]

Each enzyme that does the converting requires specific nutrients, called cofactors, including glycine, magnesium, and vitamin B6