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This method comprises contacting a cell with a ferroptosis modulator, which comprises a compound having the structure of formula (IV): Suitable and preferred compounds including preferred R 1 groups, compounds of formula (V), and SRS13-10F2, are as set forth above

H 2 S modulates hypoxia-induced pulmonary vasoconstriction by mitigating ROS production and regulating calcium signaling (Madden et al., 2012)

Apoptosis: Oxidative stress from lysosomal enzymes can induce cell apoptosis, further complicating TAO pathology by promoting tissue damage (65)