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Collectively, these findings suggest GLP-1RAs may serve as dual-purpose agents by targeting both metabolic and inflammatory components of asthma by modulating arginine metabolism, reducing oxidative stress, preserving lung epithelial integrity, and counteracting inflammation-driven lung injury, with potential mechanistic insight shown in Fig

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These drugs bind to opioid receptors and reduce withdrawal symptoms without eliciting euphoria in people with opioid dependency

doi: 10.1016/j.mrfmmm.2008.07.014