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The Synergistic Approach Rather than viewing this as an either-or decision, some practitioners recommend combining NAC with other liver-supportive nutrients for comprehensive hepatic protection

Mol Gen Genet 264:902912 Ott T, Van Dongen JT, Gunther C, Krusell L, Desbrosses G, Vigeolas H, Bock V, Czechowski T, Geigenberger P, Udvardi MK (2005) Symbiotic leghemoglobins are crucial for nitrogen fixation in legume root nodules but not for general plant growth and development

HIF-1 induces the expression of glycolytic genes, including GLUT1, HK2, PFKFB3, LDHA, and pyruvate dehydrogenase kinase (PDK), and TCA cycle suppressors (56, 57)