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Furthermore, after 24, 48, 72, and 96 h after treatment DNA damage was observed in a dose- and time-dependent manner (Patlolla et al., 2009)

As with any therapy, long-term studies are still limited, so ongoing observation and clinical research will further define its safety profile

Furthermore, Cys supplementation enhances intracellular levels of GSH, a major cellular antioxidant, which contributes to the suppression of pro-inflammatory cytokine production factors known to impair TJs integrity and increase epithelial permeability (Hasegawa et al

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