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3) Glycaemic and cardiometabolic endpoints in defined populations Some cagrilintide combination studies include participants with type 2 diabetes and report glycaemic endpoints such as HbA1c alongside weight change

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That said, the clearest human evidence so far is a small pilot where three months of B12 brought deficient older adults strength up to match non-deficient peers promising, but larger trials are the next step, especially on whether B12 supplementation helps people who arent prone to deficiencies