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After treating by ultrasonication, the supernatant was used for HPLC detection while the precipitation was dried off to obtain the wight of original mycelia

In one clinical trial evaluating its use in both conditions, carboxytherapy was associated with statistically significant improvements in clinical scores, global assessments, and dermoscopic and digital trichoscopic parameters compared with the placebo [19]

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doi: 10.1161/CIRCULATIONAHA.115.020406 8