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Lastly, fibulin 3 (FBLN3), an extracellular matrix protein, suppresses both EMT and self-renewal of the lung cancer stem cells by inhibiting the IGF-IR/PI3K/AKT/GSK3 pathway [77]

doi: 10.1016/j.exer.2007.01.017

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The hydroxyl radical typically initiates peroxidation by abstracting a hydrogen atom from a methylene carbon side chain, initially forming a carbon-centered, lipid radical and water (135)