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Prolonged intake of vitamin B6 at doses as low as 50 mg daily has been associated with peripheral neuropathy, characterised by nerve damage causing tingling and numbness

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Results The MHCII pathway is downregulated in islet macrophages of hIAPP Tg/0 mice We sought to examine the phenotype of islet macrophages exposed to islet amyloid in situ

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At higher concentrations, m was fully impaired and comparable to full m destabilization due to treatment with the protonophore FCCP

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10.1038/s41574-022-00638-x 222 VenturelliM.SchenaF.RichardsonR

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