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Description

Furthermore, the current codes are stigmatizing and reflect outdated scientific understanding of the disease processes underlying obesity

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Additionally, CYP51A1 interacts with 15 core enzymes in the cholesterol biosynthesis pathway, including HMG-CoA reductase (HMGCR), FDFT1, dehydrocholesterol reductases (DHCRs), sigma non-opioid intracellular receptor 1 (SIGMAR1), and squalene epoxidase (SQLE), further supporting its central role in maintaining lipid homeostasis [47]

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[45] (Additional file 1)

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GSK-LSD1 can inhibit KDM1A/LSD1 enzyme activity

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E., Betensky, R

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