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The overnight fast means the PM dose works in a progressively more favorable environment as the night goes on

Thereafter, the compound motor action potential (CMAP) was recorded from the same pair of electrodes after stimulating the first and second electrodes (a repetition of 1 Hz and a stimulus duration of 0.05 ms)

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[19] [21] If a dose is missed, it should be administered as soon as possible, unless it is almost time for the next scheduled dose