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Results: Meta-analysis showed a statistically significant effect of curcumin on depressive symptoms (SMD: 0.65, P = 0.01, 95% CI: 1.16 to 0.13, I 2 = 93%) and anxiety symptoms (SMD: 0.22, P = 0.01, 95% CI: 0.40 to 0.05, I 2 = 0%)

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Based on the data, we continue to believe that assignment to APC 5464 for CPT code 0817T is appropriate

reported a decreased expression of CLOCK, CRY1, PER1, and PER2 in the peripheral blood mononuclear cells of 326 PD patients compared to their healthy controls, along with a decreased concentration of melatonin [434]