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Description

Because oxidants can enhance inflammation, it is not clear if the cytokine-modulatory effects of vitamin C are due to its oxidant scavenging function or its gene regulatory cofactor functions (Song et al., 2017)

Cells were pre-treated with LPS (1 g/mL) for 30 min to induce an inflammatory state, followed by treatment with varying concentrations of APE (62.5, 125, 250, 500, 1000, and 2000 g/mL) for 24 h