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Pyrethroid carboxylesterase PytH from Sphingobium faniae JZ-2: structure and catalytic mechanism

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(2003) found that after a sciatic nerve crush injury in transgenic mice expressing the human IGF-1 transgene, there is an increase in the number of neurofilaments staining the axons in muscle and an accelerated return of nerve conduction velocity

demonstrated that the use of structure-based design of a self-assembling protein nanoparticle presenting a pre-fusion-stabilized DS-Cav1 in a repetitive array on the nanoparticle exterior induced neutralizing antibody responses up to tenfold higher than trimeric DS-Cav1 alone 260

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