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Description

As a hexapeptide derivative, Dihexa has drawn significant attention in the scientific community due to its capacity to influence molecular pathways associated with synaptic plasticity and cognitive function

Abnormalities in the GH/IGF-I axis have also been observed in patients with type 2 diabetes (T2D) (50)

The restraints were derived from (i) NOE restraints from intermolecular and intramolecular cross-peaks in NOESY spectra (described in NMR spectroscopy section), (ii) TALOS derived p53 TAD2 and FOXO4-DRI backbone dihedral angles, (iii) hydrogen bond restraints (regions p53 residues 4752, FOXO4-DRI residues 918