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Declining NAD+ impairs energy, metabolism, skin health, and immunity, accelerating biological aging.[12][13] Research indicates that this loop can be interrupted by boosting NAD+, potentially reversing aspects of biological age as measured by epigenetic clocks

Unlike full-length growth hormone, which can stimulate appetite through IGF-1 production and growth hormone receptor activation, AOD-9604 does not activate the growth hormone/IGF-1 pathway

For oral administration, clinical trials have studied doses ranging from 1-30 mg daily, with typical protocols using 1-2 mg per dose on an empty stomach

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