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In females, 10 biochemical pathways were significantly dysregulated ( Fig

On the flip side, osteoclasts rely on serine metabolism for their bone-resorbing function: deletion of PHGDH in osteoclast progenitors was shown to impair osteoclastogenesis and resulted in increased bone mass in mice [14]

FIGURE 1 Under physiological conditions, LLPS of -synuclein is prevented by -synuclein, a related protein of the synuclein family which is present at the presynaptic terminals at a similar concentration as that of -synuclein (around 50 M)

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Azacitidine with or without eltrombopag for first-line treatment of intermediate- or high-risk MDS with thrombocytopenia