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CAFs can secrete lipids such as lysophosphatidylcholine (LPA) and promote PDAC cell progression and AKT activation through the autotaxin-LPA axis [195]

Most of the antiinflammatory activities of WS have been attributed by researchers to withanolides, particularly Withaferin A [173, 174]

Evidence that niacin inhibits acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids

After multiple reviews of these articles, 100 articles met the relevance criteria and were selected

Research involving human endothelial cells, U -931 cells (human histiocytic lymphoma), and hepatic G2 cells has also highlighted particular effects of PKC isozymes at various phases of atherosclerosis advancement [47]