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Description

Immunity 48(4):787-798.e4

Cholesterol trafficking and endolysosome dysfunction The intricate relationship between cholesterol metabolism, endolysosome dysfunction and AD highlights the importance of cellular pathways that regulate intracellular trafficking, lipid metabolism, and APP processing in AD pathogenesis

Understanding the full potential of each molecule in improving both metabolic and mechanical obesity-related complications through research will support personalised pharmacotherapy choices

However, in the case of three discrepancies, the 1-year, 3-year, and 5-year survival rates were 52.4%, 28.6%, and 28.6%, respectively

Structural prediction of NES1 and NES2 The structural models of the nuclear export signal (NES) peptides NES1 and NES2 were obtained using the I-TASSER (Iterative Threading ASSEmbly Refinement) server [27]