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Under the iron-rich, ROS-prone conditions characteristic of lesions, this perturbation engages a coordinated program of RCD across intersecting pathwaysnot only ferroptosis but also necroptotic and pyroptotic signalingwhile ferritin handling and mitophagy status further skew redox homeostasis toward irreversible injury in EESCs

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For instance, it actively improves lipid profiles by upregulating the expression of Low-Density Lipoprotein Receptors (LDLR) on the surface of liver cells