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Their mechanism of action involves blocking cholinergic receptors, thereby reducing the effect of acetylcholine in the nigrostriatal pathway to restore the balance between dopamine and cholinergic neurotransmitters, which underlies their therapeutic effect [131]

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New variant of cytochrome b5 reductase deficiency (b5Rkurashaki) in red cells, platelets, lymphocytes and cultured fibroblasts with congenital methemoglobinemia, mental and neurological retardation and skeletal abnormalities

Cognitive decline and neuropsychiatric symptoms The degeneration of dopaminergic neurons in the basal ganglia disrupts executive functions, leading to difficulties in planning, problem-solving, and multitasking